Progressive jaundice, draining ears and seborrheic dermatitis in a 25-month-old boy
( P
age 1/2)
Prepared by...
Pimlak Charoenkwan, M.D.
Department of Pediatrics, Chiang Mai University



     of hill tribe origin was brought to the pediatric department with a history of progressive
jaundice, draining ears and seborrheic dermatitis
for 6 months. He was the sixth child of the
family. There was no history of consanguinity and the rest of the family were healthy. He had been
treated for chronic otitis media at a community hospital without improvement. On physical
examination, he was below the third percentile for both weight and height. He had moderate
jaundice. Numerous scaly erythematous papules were present at face, especially below hairline,
anterior chest wall and upper two thirds of back. He also had hypertrophic, friable gingiva with
signs of inflammation and contact bleeding. Both fingernails and toenails were thickened with
hemorrhagic lesions in the nail plates and subungual hyperkeratosis. A few tiny pustules were
observed in  periungual region and under nail plates. Generalized lymphadenopathy and hepatosplenomegaly were noted. The cardiovascular and respiratory systems were normal. The
neurological examination was normal. Skin, gum and nail lesions are shown as figure 1-4.
     

  Figure 1

Figure 2
mvc-003f.jpg (43066 bytes)
Figure 3 Figure 4
 
1. What is your diagnosis?
2.  What should be done for further investigations?
 
      Click here for answers